SLC46A1 Rabbit pAb
Catalog No:AB-A7397
Manufacturer:ABclonal
Synonyms:SLC46A1;G21;HCP1;PCFT
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €325,00
Product Name: | SLC46A1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes, optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a heme transporter in duodenal enterocytes, and potentially in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene are associated with autosomal recessive hereditary folate malabsorption disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human SLC46A1 (NP_001229295.1). |
Gene ID: | 113235 |
Swiss prot: | Q96NT5 |
Molecular weight: | 46kDa/49kDa |
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