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Western blot analysis of extracts of various cell lines, using SIM2 antibody (A15098) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
SIM2 Rabbit pAb
Catalog No：AB-A15098
Manufacturer：ABclonal
Synonyms：SIM2;HMC13F06;HMC29C01;SIM;bHLHe15
Applications：WB,IHC
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | SIM2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 342-525 of human SIM2 (NP_033664.2). |
| Gene ID: | 6493 |
| Swiss prot: | Q14190 |
| Molecular weight: | 63kDa/73kDa |
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