Western blot analysis of extracts of various cell lines, using SGCG antibody (A10540) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
SGCG Rabbit pAb
Catalog No:AB-A10540
Manufacturer:ABclonal
Synonyms:SGCG;35DAG;A4;DAGA4;DMDA;DMDA1;LGMD2C;MAM;SCARMD2;SCG3;gamma-SG
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | SGCG Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 72-291 of human SGCG (NP_000222.1). |
Gene ID: | 6445 |
Swiss prot: | Q13326 |
Molecular weight: | 32kDa |
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