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Western blot analysis of extracts of various cell lines, using SERCA2/ATP2A2 Rabbit mAb (A11692) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
SERCA2/ATP2A2 Rabbit mAb
Catalog No：AB-A11692
Manufacturer：ABclonal
Synonyms：ATP2B, DAR, DD, SERCA2
Applications：WB,IP
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | SERCA2/ATP2A2 Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2008] |
| Immunogen: | A synthesized peptide derived from human SERCA2/ATP2A2 |
| Gene ID: | 488 |
| Swiss prot: | P16615 |
| Molecular weight: | 110,140kDa |
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