Ser/thr-PP2A activator (PTPA) Rabbit pAb
Catalog No:AB-A1912
Manufacturer:ABclonal
Synonyms:PTPA;PP2A;PPP2R4;PR53
Applications:IHC,IF
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | Ser/thr-PP2A activator (PTPA) Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B’/PR61, and B”/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B’ family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human Ser/thr-PP2A activator (PTPA) (NP_821067.1). |
Gene ID: | 5524 |
Swiss prot: | Q15257 |
Molecular weight: | 31kDa/33kDa/36kDa/40kDa |
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