SEMA6D Rabbit pAb
Catalog No：AB-A14935
Manufacturer：ABclonal
Synonyms：SEMA6D
Applications：WB
Reactivity：Mouse
Host：Rabbit
Conjugate：No
€65,00 – €325,00
| Product Name: | SEMA6D Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-110 of human SEMA6D (NP_705871.1). |
| Gene ID: | 80031 |
| Swiss prot: | Q8NFY4 |
| Molecular weight: | 54kDa/67kDa/111-119kDa |
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