Desmethyl Erlotinib hydrochloride [Cas No. 183320-51-6]
Catalog No:TA-T6619
Manufacturer:TargetMol
Synonyms:OSI 420,OSI-420,CP-473420,Desmethyl Erlotinib,DesMethyl Erlotinib (CP-473420) HCl
CAS No.:183320-51-6
Formula:C21H21N3O4﹞HCl
MWt:415.87
€54,00 – €758,00
Name: | OSI420 |
Category: | Biochemicals |
Description: | OSI-420 (Desmethyl Erlotinib, CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for human EGFR and EGFR autophosphorylation in tumor cells. |
Pathway: | Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors |
Target: | EGFR inhibitor |
Receptor: | EGFR |
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