PHA-680632 [Cas No. 398493-79-3]
Catalog No：TA-T6338
Manufacturer：TargetMol
Synonyms：PHA 680632,PHA-680632
CAS No.：398493-79-3
Formula：C28H35N7O2
MWt：501.62
€43,00 – €1.365,00
| Name: | PHA680632 |
| Category: | Biochemicals |
| Description: | PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3. |
| Pathway: | Cell Cycle/Checkpoint, Angiogenesis, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors |
| Target: | Aurora Kinase inhibitor, FGFR inhibitor, PLK inhibitor |
| Receptor: | Aurora A, Aurora B, Aurora C, FGFR1, PLK1 |
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