Western blot analysis of extracts of various cell lines, using SDHB Rabbit mAb (A1809) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3min.
SDHB Rabbit mAb
Catalog No:AB-A1809
Manufacturer:ABclonal
Synonyms:CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | SDHB Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008] |
Immunogen: | A synthesized peptide derived from human SDHB |
Gene ID: | 6390 |
Swiss prot: | P21912 |
Molecular weight: | 32kDa |
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