(S)-Afatinib [Cas No. 439081-18-2]
Catalog No：TA-T2303
Manufacturer：TargetMol
Synonyms：BIBW2992
CAS No.：439081-18-2
Formula：C24H25ClFN5O3
MWt：485.94
€29,00 – €603,00
| Name: | Afatinib |
| Category: | Biochemicals |
| Description: | Afatinib (BIBW 2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, EGFR (L858R), EGFR (L858R/T790M), HER2, and HER4, respectively. |
| Pathway: | Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors |
| Target: | EGFR, HER |
| Receptor: | EGFR (L858R), EGFR (L858R/T790M), EGFR (wt), HER2, HER4 |
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