Niraparib [Cas No. 1038915-60-4]
Catalog No：TA-T3231
Manufacturer：TargetMol
Synonyms：MK-4827
CAS No.：1038915-60-4
Formula：C19H20N4O
MWt：320.39
€48,00 – €573,00
| Name: | Niraparib |
| Category: | Biochemicals |
| Description: | MK-4827(Niraparib) is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM, with great activity in cancer cells with mutant BRCA-1 and BRCA-2, >330-fold selective against PARP3, V-PARP and Tank1. |
| Pathway: | Chromatin/Epigenetic, Others, DNA Damage/DNA Repair |
| Target: | Others inhibitor, PARP inhibitor |
| Receptor: | TANK-1, PARP1, PARP2, PARP3, V-PARP |
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