Western blot analysis of extracts of various cell lines, using RPA70 antibody (A9841) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
RPA70 Rabbit pAb
Catalog No:AB-A9841
Manufacturer:ABclonal
Synonyms:RPE65;BCO3;LCA2;RP20;mRPE65;rd12;sRPE65
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | RPA70 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 274-533 of human RPA70 (NP_000320.1). |
Gene ID: | 6121 |
Swiss prot: | Q16518 |
Molecular weight: | 60kDa |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No:AB-A13256
Manufacturer:ABclonal
Synonyms:LRAT;LCA14
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A13175
Manufacturer:ABclonal
Synonyms:LRAT;LCA14
Applications:WB
Reactivity:Human,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A13011
Manufacturer:ABclonal
Synonyms:CEL;BAL;BSDL;BSSL;CELL;CEase;FAP;FAPP;LIPA;MODY8
Applications:WB
Reactivity:Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A12495
Manufacturer:ABclonal
Synonyms:RBP4;MCOPCB10;RDCCAS
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A11737
Manufacturer:ABclonal
Synonyms:VDR;NR1I1;PPP1R163
Applications:WB
Reactivity:Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A10709
Manufacturer:ABclonal
Synonyms:CLDN12
Applications:WB
Reactivity:Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €325,00