Western blot analysis of extracts of various cell lines, using Rnf170 antibody (A15196) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
Rnf170 Rabbit pAb
Catalog No:AB-A15196
Manufacturer:ABclonal
Synonyms:RNF170;ADSA;SNAX1;Rnf170
Applications:WB
Reactivity:Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | Rnf170 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of mouse Rnf170 (NP_084241.1). |
Gene ID: | 77733 |
Swiss prot: | |
Molecular weight: | 16kDa/24kDa/28kDa/33kDa |
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