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Western blot analysis of extracts of various cell lines, using RASSF1 antibody (A1203) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.
RASSF1 Rabbit pAb
Catalog No：AB-A1203
Manufacturer：ABclonal
Synonyms：RASSF1;123F2;NORE2A;RASSF1A;RDA32;REH3P21
Applications：WB,IF
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | RASSF1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 101-340 of human RASSF1 (NP_009113.3). |
| Gene ID: | 11186 |
| Swiss prot: | Q9NS23 |
| Molecular weight: | 8kDa/9kDa/16kDa/21kDa/31kDa/38kDa/39kDa |
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