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Western blot analysis of extracts of mouse brain, using RASGRF1 antibody (A6964) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded human stomach using RASGRF1 antibody (A6964) at dilution of 1:100 (40x lens).
RASGRF1 Rabbit pAb
Catalog No：AB-A6964
Manufacturer：ABclonal
Synonyms：RASGRF1;CDC25;CDC25L;GNRP;GRF1;GRF55;H-GRF55;PP13187;ras-GRF1
Applications：WB,IHC,IF
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | RASGRF1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human RASGRF1 (NP_001139120.1). |
| Gene ID: | 5923 |
| Swiss prot: | Q13972 |
| Molecular weight: | 55kDa/143kDa/145kDa |
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