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Western blot analysis of extracts of Mouse lung, using RASD2 antibody (A17367) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
RASD2 Rabbit pAb
Catalog No：AB-A17367
Manufacturer：ABclonal
Synonyms：Rhes;TEM2;MGC:4834;RASD2
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | RASD2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients. |
| Immunogen: | Recombinant protein of human RASD2. |
| Gene ID: | 23551 |
| Swiss prot: | Q96D21 |
| Molecular weight: | 30kDa |
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