Western blot analysis of extracts of various cell lines, using RAIDD/RAIDD/CRADD antibody (A1124) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
RAIDD/CRADD Rabbit pAb
Catalog No:AB-A1124
Manufacturer:ABclonal
Synonyms:CRADD;MRT34;RAIDD
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | RAIDD/CRADD Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human RAIDD/RAIDD/CRADD (NP_003796.1). |
Gene ID: | 8738 |
Swiss prot: | P78560 |
Molecular weight: | 11kDa/22kDa |
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