Phenoxybenzamine hydrochloride [Cas No. 63-92-3]
Catalog No:TA-T1158
Manufacturer:TargetMol
Synonyms:Phenoxybenzamine HCl,NSC 37448,NCI-c01661
CAS No.:63-92-3
Formula:C18H23Cl2NO
MWt:340.3
€30,00 – €100,00
Name: | Phenoxybenzamine hydrochloride |
Category: | Biochemicals |
Description: | Phenoxybenzamine Hydrochloride is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non-selectively and irreversibly blocks the postsynaptic alpha-adrenergic receptor in smooth muscle, thereby preventing vasoconstriction, relieving vasospasms, and decreasing peripheral resistance. Reflex tachycardia may occur and may be enhanced by blockade of alpha-2 receptors which enhances norepinephrine release. Phenoxybenzamine is reasonably anticipated to be a human carcinogen. |
Pathway: | GPCR/G Protein, Neuroscience |
Target: | Adrenergic Receptor antagonist, CaMK inhibitor |
Receptor: | α-adrenergic receptor, CAM |
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