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Western blot analysis of extracts of various cell lines, using QPRT antibody (A14349) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
QPRT Rabbit pAb
Catalog No：AB-A14349
Manufacturer：ABclonal
Synonyms：QPRT;HEL-S-90n;QPRTase
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | QPRT Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer’s disease, and Huntington’s disease. Alternative splicing results in multiple transcript variants. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-297 of human QPRT (NP_055113.2). |
| Gene ID: | 23475 |
| Swiss prot: | Q15274 |
| Molecular weight: | 30kDa |
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