Western blot analysis of extracts of various cell lines, using PTRF antibody (A18331) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
PTRF Rabbit pAb
Catalog No:AB-A18331
Manufacturer:ABclonal
Synonyms:CAVIN1;CAVIN;CGL4;FKSG13;PTRF;cavin-1
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | PTRF Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3′ end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy. |
Immunogen: | Recombinant protein of human PTRF. |
Gene ID: | 284119 |
Swiss prot: | Q6NZI2 |
Molecular weight: | 43kDa |
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