Western blot analysis of extracts of various cell lines, using PTPRN2 antibody (A14774) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
PTPRN2 Rabbit pAb
Catalog No:AB-A14774
Manufacturer:ABclonal
Synonyms:PTPRN2;IA-2beta;IAR;ICAAR;PTPRP;R-PTP-N2
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | PTPRN2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-242 of human PTPRN2 (NP_570858.2). |
Gene ID: | 5799 |
Swiss prot: | Q92932 |
Molecular weight: | 108kDa/109kDa/111kDa/114kDa |
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