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Western blot analysis of extracts of various cell lines, using PTP4A2 antibody (A15335) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
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Immunohistochemistry of paraffin-embedded human colon using PTP4A2 antibody (A15335) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat kidney using PTP4A2 antibody (A15335) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse lung using PTP4A2 antibody (A15335) at dilution of 1:100 (40x lens).
PTP4A2 Rabbit pAb
Catalog No：AB-A15335
Manufacturer：ABclonal
Synonyms：PTP4A2;HH13;HH7-2;HU-PP-1;OV-1;PRL-2;PRL2;PTP4A;PTPCAAX2;ptp-IV1a;ptp-IV1b
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | PTP4A2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-100 of human PTP4A2 (NP_536316.1). |
| Gene ID: | 8073 |
| Swiss prot: | Q12974 |
| Molecular weight: | 9kDa/15kDa/16kDa/19kDa |
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