PTGIS Rabbit pAb
Catalog No:AB-A20443
Manufacturer:ABclonal
Synonyms:CYP8; PGIS; PTGI; CYP8A1
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€110,00 – €325,00
Product Name: | PTGIS Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 151-500 of human PTGIS (NP_000952.1). |
Gene ID: | 5740 |
Swiss prot: | Q16647 |
Molecular weight: | 57kDa |
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