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Western blot analysis of extracts of various cell lines, using PSEN2 antibody (A7719) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded rat heart using PSEN2 antibody (A7719) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human kidney using PSEN2 antibody (A7719) at dilution of 1:100 (40x lens).
PSEN2 Rabbit pAb
Catalog No：AB-A7719
Manufacturer：ABclonal
Synonyms：PSEN2;AD3L;AD4;CMD1V;PS2;STM2
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | PSEN2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Alzheimer’s disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor such that, they either directly regulate gamma-secretase activity, or themselves act are protease enzymes. Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified. |
| Immunogen: | Recombinant protein of human PSEN2. |
| Gene ID: | 5664 |
| Swiss prot: | P49810 |
| Molecular weight: | 46kDa/50kDa |
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Catalog No：AB-A0146
Manufacturer：ABclonal
Synonyms：SLC9A3R1;EBP50;NHERF;NHERF-1;NHERF1;NPHLOP2
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0098
Manufacturer：ABclonal
Synonyms：ATP2B;DAR;DD;SERCA2;ATP2A2/SERCA2;ATP2A2
Applications：WB,IHC
Reactivity：Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0059
Manufacturer：ABclonal
Synonyms：BSCL3;CGL3;LCCNS;MSTP085;PPH3;VIP21;CAV1
Applications：IF
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0040
Manufacturer：ABclonal
Synonyms：MET;AUTS9;DFNB97;HGFR;RCCP2;c-Met
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0008
Manufacturer：ABclonal
Synonyms：10q23del;BZS;CWS1;DEC;GLM2;MHAM;MMAC1;PTEN1;TEP1;PTEN;PTENbeta
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0003
Manufacturer：ABclonal
Synonyms：OSRC;PPP1R130;RB;p105-Rb;pRb;pp110;RB1;Rb
Applications：WB,IF
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €485,00