PrP (106-126)
Catalog No:CP-PRPR-001
Manufacturer:CPC Scientific
Size:1 mg
CAS No.:148439-49-0
Formula:C80H138 N26O24S 2
MWt:1,912
€139,00
Product Name: | PrP (106-126) |
Category: | Peptides |
Three letter sequence: | Lys-Thr-Asn- Met-Lys-His- Met-Ala-Gly- Ala-Ala-Ala- Ala-Gly-Ala- Val-Val-Gly- Gly-Leu-Gly Trifluoroacet ate salt |
One letter sequence: | KTNMKHMAGA AAAGAVVGGL G |
Description: | This peptide increases membrane microviscosity, intracellular Ca2+ concentration and cell migration in circulating leucocytes, and oxygen production in monocytes and neutrophils. It also induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell lines. PrP (106鈥 126) stimulates leucocyte migration in a dose-dependent manner. |
Literature References: | Diomede, L. et al. Biochem. J. 320, 563 (1996) Florio, T. et al. J. Neurosci. Res. 54, 341 (1998). |
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