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Western blot analysis of extracts of various cell lines, using Proprotein Convertase 9(PCSK9) antibody (A7860) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
Proprotein Convertase 9(PCSK9) Rabbit pAb
Catalog No：AB-A7860
Manufacturer：ABclonal
Synonyms：PCSK9;FH3;HCHOLA3;LDLCQ1;NARC-1;NARC1;PC9
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | Proprotein Convertase 9(PCSK9) Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants. |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 600 to the C-terminus of human Proprotein Convertase 9(PCSK9) (NP_777596.2). |
| Gene ID: | 255738 |
| Swiss prot: | Q8NBP7 |
| Molecular weight: | 20kDa/74kDa |
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