GI254023X [Cas No. 260264-93-5]
Catalog No:TA-T7522
Manufacturer:TargetMol
CAS No.:260264-93-5
Formula:C21H33N3O4
MWt:391.5
€87,00 – €987,00
Name: | GI 254023X |
Category: | Biochemicals |
Description: | GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM) with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE). GI254023X can remarkably inhibit the proliferation and induce the apoptosis of H929 cells. Its mechanism may be associated with inbihition of Notch1 activation. |
Pathway: | Proteases & Proteasome, Immunology & Inflammation |
Target: | MMP, Immunology & Inflammation related |
Receptor: | MMP-9, ADAM10 |
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