PRDM16 Rabbit pAb
Catalog No:AB-A18633
Manufacturer:ABclonal
Synonyms:PRDM16; CMD1LL; KMT8F; LVNC8; MEL1; PFM13; PR/SET domain 16
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €325,00
Product Name: | PRDM16 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Immunogen: | Recombinant protein of human PRDM16. |
Gene ID: | 63976 |
Swiss prot: | Q9HAZ2 |
Molecular weight: | 120kDa/138kDa/140kDa |
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