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Western blot analysis of extracts of various cell lines, using POT1 antibody (A1491) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
POT1 Rabbit pAb
Catalog No：AB-A1491
Manufacturer：ABclonal
Synonyms：POT1;CMM10;GLM9;HPOT1
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | POT1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 497-634 of human POT1 (NP_056265.2). |
| Gene ID: | 25913 |
| Swiss prot: | Q9NUX5 |
| Molecular weight: | 60kDa/71kDa |
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