OSI-027 [Cas No. 936890-98-1]
Catalog No：TA-T6319
Manufacturer：TargetMol
Synonyms：OSI 027,OSI-027,ASP4786
CAS No.：936890-98-1
Formula：C21H22N6O3
MWt：406.44
€35,00 – €817,00
| Name: | OSI027 |
| Category: | Biochemicals |
| Description: | OSI-027 is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, and more than 100-fold selectivity observed for mTOR than PI3Kα, PI3Kβ, PI3Kγ or DNA-PK. Phase 1. |
| Pathway: | DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling |
| Target: | DNA-PK inhibitor, mTOR inhibitor, PI3K inhibitor |
| Receptor: | DNA-PK, mTOR, mTORC1, mTORC2, PI3Kγ |
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