Western blot analysis of extracts of various cell lines, using PMS1 antibody (A2183) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
PMS1 Rabbit pAb
Catalog No:AB-A2183
Manufacturer:ABclonal
Synonyms:PMS1;HNPCC3;MLH2;PMSL1;hPMS1
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | PMS1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 405-619 of human PMS1 (NP_000525.1). |
Gene ID: | 5378 |
Swiss prot: | P54277 |
Molecular weight: | 62kDa/86kDa/101kDa/105kDa |
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