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Western blot analysis of extracts of various cell lines, using PLC gamma 2 (PLC gamma 2 (PLCG2)) antibody (A2182) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.
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Immunohistochemistry of paraffin-embedded mouse heart using PLC gamma 2 (PLC gamma 2 (PLCG2)) antibody (A2182) at dilution of 1:100 (40x lens).
PLC gamma 2 (PLCG2) Rabbit pAb
Catalog No：AB-A2182
Manufacturer：ABclonal
Synonyms：PLCG2;APLAID;FCAS3;PLC-IV;PLC-gamma-2
Applications：WB,IHC,IF
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | PLC gamma 2 (PLCG2) Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PLC gamma 2 (PLC gamma 2 (PLCG2)) (NP_002652.2). |
| Gene ID: | 5336 |
| Swiss prot: | P16885 |
| Molecular weight: | 147kDa |
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