Western blot analysis of extracts of Raji cells, using PLC gamma 2 (PLC gamma 2 (PLCG2)) Rabbit mAb (A5182) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
PLC gamma 2 (PLCG2) Rabbit mAb
Catalog No:AB-A5182
Manufacturer:ABclonal
Synonyms:APLAID, FCAS3, PLC-IV, PLC-gamma-2
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | PLC gamma 2 (PLCG2) Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014] |
Immunogen: | A synthesized peptide derived from human PLC gamma 2 (PLC gamma 2 (PLCG2)) |
Gene ID: | 5336 |
Swiss prot: | P16885 |
Molecular weight: | 148kDa |
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