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Western blot analysis of extracts of various cell lines, using PLAU antibody (A2181) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
PLAU Rabbit pAb
Catalog No：AB-A2181
Manufacturer：ABclonal
Synonyms：PLAU;ATF;BDPLT5;QPD;UPA;URK;u-PA;urokinase
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | PLAU Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer’s disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-180 of human PLAU (NP_002649.1). |
| Gene ID: | 5328 |
| Swiss prot: | P00749 |
| Molecular weight: | 46kDa/48kDa |
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