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Western blot analysis of extracts of various cell lines, using PKC alpha pAb (A11107) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
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Immunohistochemistry of paraffin-embedded human colon carcinoma using PKC alpha antibody (A11107) at dilution of 1:100 (40x lens).
PKC alpha Rabbit mAb
Catalog No：AB-A11107
Manufacturer：ABclonal
Synonyms：PRKCA;AAG6;PKC-alpha;PKCA;PRKACA;PKC alpha
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €605,00
| Product Name: | PKC alpha Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. |
| Immunogen: | Recombinant protein of human PKC alpha . |
| Gene ID: | 5578 |
| Swiss prot: | P17252 |
| Molecular weight: | 76kDa |
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