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Western blot analysis of extracts of various cell lines, using PIK3C2A antibody (A8526) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded mouse heart using PIK3C2A antibody (A8526) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat heart using PIK3C2A antibody (A8526) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human liver damage using PIK3C2A antibody (A8526) at dilution of 1:100 (40x lens).
PIK3C2A Rabbit pAb
Catalog No：AB-A8526
Manufacturer：ABclonal
Synonyms：PIK3C2A;CPK;PI3-K-C2(ALPHA);PI3-K-C2A;PI3K-C2-alpha;PI3K-C2alpha
Applications：WB,IHC,IF,IP
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | PIK3C2A Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PIK3C2A (NP_002636.2). |
| Gene ID: | 5286 |
| Swiss prot: | O00443 |
| Molecular weight: | 53kDa/190kDa |
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