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Western blot analysis of extracts of various cell lines, using PIDD antibody (A4831) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
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Immunohistochemistry of paraffin-embedded human lung cancer using PIDD antibody (A4831) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat brain using PIDD antibody (A4831) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse brain using PIDD antibody (A4831) at dilution of 1:100 (40x lens).
PIDD Rabbit pAb
Catalog No：AB-A4831
Manufacturer：ABclonal
Synonyms：PIDD1;LRDD;PIDD
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | PIDD Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human PIDD (NP_665893.2). |
| Gene ID: | 55367 |
| Swiss prot: | Q9HB75 |
| Molecular weight: | 33kDa/37kDa/58kDa/66kDa/82kDa/97kDa/99kDa |
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