CMPD101 [Cas No. 865608-11-3]
Catalog No:TA-T14989
Manufacturer:TargetMol
CAS No.:865608-11-3
Formula:C24H21F3N6O
MWt:466.46
€107,00 – €977,00
Name: | CMPD101 |
Category: | Biochemicals |
Description: | CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM). Which can be used for the study of heart failure. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCα with IC50s of 3.1 μM , 2.3 μM, 1.4 μM and 8.1 μM, respectively. |
Pathway: | Cell Cycle/Checkpoint,Chromatin/Epigenetic,Cytoskeletal Signaling,GPCR/G Protein,Stem Cells |
Target: | GRK,PKC,ROCK |
Receptor: | GRK2,GRK3,PKCα,ROCK2 |
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