Western blot analysis of extracts of various cell lines, using PHOX2B Rabbit mAb (A6816) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3min.
PHOX2B Rabbit mAb
Catalog No:AB-A6816
Manufacturer:ABclonal
Synonyms:NBLST2, NBPhox, PMX2B
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | PHOX2B Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome. [provided by RefSeq, Jul 2016] |
Immunogen: | A synthesized peptide derived from human PHOX2B |
Gene ID: | 8929 |
Swiss prot: | Q99453 |
Molecular weight: | 35kDa |
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