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Western blot analysis of extracts of various cell lines, using PHOX2B Rabbit mAb (A6816) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3min.
PHOX2B Rabbit mAb
Catalog No：AB-A6816
Manufacturer：ABclonal
Synonyms：NBLST2, NBPhox, PMX2B
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | PHOX2B Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome. [provided by RefSeq, Jul 2016] |
| Immunogen: | A synthesized peptide derived from human PHOX2B |
| Gene ID: | 8929 |
| Swiss prot: | Q99453 |
| Molecular weight: | 35kDa |
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