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Immunohistochemistry of paraffin-embedded human colon carcinoma using Phospho-β-Catenin-S33/S37/T41 antibody (AP0524) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat skin using Phospho-β-Catenin-S33/S37/T41 antibody (AP0524) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse kidney using Phospho-β-Catenin-S33/S37/T41 antibody (AP0524) at dilution of 1:100 (40x lens).
Phospho-β-Catenin-S33/S37/T41 Rabbit pAb
Catalog No：AB-AP0524
Manufacturer：ABclonal
Synonyms：CTNNB;MRD19;armadillo;beta Catenin;CTNNB1
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €410,00
| Product Name: | Phospho-尾-Catenin-S33/S37/T41 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. |
| Immunogen: | A synthetic phosphorylated peptide around S33 & T41 of human beta Catenin (NP_001091679). |
| Gene ID: | 1499 |
| Swiss prot: | P35222 |
| Molecular weight: | 9kDa/85kDa |
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