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Western blot analysis of extracts of NIH3T3 cells, using Phospho-TrkA-Y490 antibody (AP0492).|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.
Phospho-TrkA-Y490 Rabbit pAb
Catalog No：AB-AP0492
Manufacturer：ABclonal
Synonyms：NTRK1;MTC;TRK;TRK1;TRKA;Trk-A;p140-TrkA
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €410,00
| Product Name: | Phospho-TrkA-Y490 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding Y490 of human Phospho-TrkA-Y490 |
| Gene ID: | 4914 |
| Swiss prot: | P04629 |
| Molecular weight: | 77kDa/83kDa/86kDa/87kDa |
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