Western blot analysis of extracts of THP-1 cells, using Phospho-TBK1/NAK-S172 pAb (AP0847) at 1:1000 dilution.THP-1 cells were treated by LPS (1 μg/mL) at 37℃ for 6 hours.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
Phospho-TBK1/NAK-S172 Rabbit pAb
Catalog No:AB-AP0847
Manufacturer:ABclonal
Synonyms:TBK1;FTDALS4;NAK;T2K
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €410,00
Product Name: | Phospho-TBK1/NAK-S172 Rabbit pAb |
Category: | Phosphorylated Antibodies |
Description: | The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. |
Immunogen: | A synthetic phosphorylated peptide around S172 of human TBK1/NAK (NP_037386.1). |
Gene ID: | 29110 |
Swiss prot: | Q9UHD2 |
Molecular weight: | 83kDa |
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