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Western blot analysis of extracts from HeLa cells, using Phospho-STAT6-Y641 antibody (AP0456).|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.
Phospho-STAT6-Y641 Rabbit pAb
Catalog No：AB-AP0456
Manufacturer：ABclonal
Synonyms：D12S1644;IL-4-STAT;STAT6B;STAT6C;STAT6
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €410,00
| Product Name: | Phospho-STAT6-Y641 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants. |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding Y641 of human STAT6 |
| Gene ID: | 6778 |
| Swiss prot: | P42226 |
| Molecular weight: | 74kDa/81kDa/94kDa |
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