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Immunohistochemistry of paraffin-embedded rat pancreas using Phospho-Rb-S780 antibody (AP0117) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human colon using Phospho-Rb-S780 antibody (AP0117) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse liver using Phospho-Rb-S780 antibody (AP0117) at dilution of 1:100 (40x lens).
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Western blot analysis of extracts of C6 cells, using Phospho-RB-S780 Rabbit mAb (AP0117) at 1:1000 dilution.C6 cells were treated by 10% FBS at 37℃ for 30 minutes after serum-starvation overnight|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
Phospho-RB-S780 Rabbit mAb
Catalog No：AB-AP0117
Manufacturer：ABclonal
Synonyms：OSRC;PPP1R130;RB;p105-Rb;pRb;pp110;RB1;Rb
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €325,00
| Product Name: | Phospho-RB-S780 Rabbit mAb |
| Category: | Phosphorylated Antibodies |
| Description: | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008] |
| Immunogen: | A phospho synthetic peptide corresponding to residues surrounding S780 of human RB. |
| Gene ID: | 5925 |
| Swiss prot: | P06400 |
| Molecular weight: | 106kDa |
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