.jpg)
Western blot analysis of extracts of Jurkat cells, using Phospho-PTK2B-Y402 antibody (AP0214) at 1:1000 dilution.Jurkat cells were treated by 10% FBS at 37℃ for 30 minutes after serum-starvation overnight.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 180s.
.jpg)
Immunohistochemistry of paraffin-embedded human breast carcinoma using Phospho-PTK2B-Y402 antibody (AP0214).
Phospho-PTK2B-Y402 Rabbit pAb
Catalog No：AB-AP0214
Manufacturer：ABclonal
Synonyms：PTK2B;CADTK;CAKB;FADK2;FAK2;PKB;PTK;PYK2;RAFTK;Pyk2
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€150,00 – €410,00
| Product Name: | Phospho-PTK2B-Y402 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding Y402 of human PTK2B |
| Gene ID: | 2185 |
| Swiss prot: | Q14289 |
| Molecular weight: | 111kDa/115kDa |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No：AB-AP0023
Manufacturer：ABclonal
Synonyms：EGFR;ERBB;ERBB1;HER1;NISBD2;PIG61;mENA
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €410,00
Catalog No：AB-AP0020
Manufacturer：ABclonal
Synonyms：CRE-BP1;CREB-2;CREB2;HB16;TREB7;ATF2
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €410,00
Catalog No：AB-AP0013
Manufacturer：ABclonal
Synonyms：CCNE1;CCNE;pCCNE1;cyclin E1
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €410,00
Catalog No：AB-AP0009
Manufacturer：ABclonal
Synonyms：BAD;BBC2;BCL2L8;Bad
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €410,00
Catalog No：AB-AP0006
Manufacturer：ABclonal
Synonyms：AAA;ABETA;ABPP;AD1;APPI;CTFgamma;CVAP;PN-II;PN2;Amyloid beta A4;APP;Aβ42;preA4
Applications：WB
Reactivity：Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €410,00
Catalog No：AB-AP0003
Manufacturer：ABclonal
Synonyms：ABL;JTK7;p150;c-ABL;v-abl;CHDSKM;c-ABL1;ABL1;c-Abl;bcr/abl
Applications：WB,IF
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €410,00