Western blot analysis of extracts of 293T cells, using Phospho-INSR-Y1189/Y1190 + IGF1R-Y1165/Y1166 antibody (AP1086) at 1:1000 dilution or IGF1R antibody (A0243).293T cells were treated by IGF-1 (50 ng/mL) at 37℃ for 5 minutes after serum-starvation overnight.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
Phospho-INSR-Y1189/Y1190 + IGF1R-Y1165/Y1166 Rabbit pAb
Catalog No:AB-AP1086
Manufacturer:ABclonal
Synonyms:IGF1R/INSR
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €410,00
Product Name: | Phospho-INSR-Y1189/Y1190 + IGF1R-Y1165/Y1166 Rabbit pAb |
Category: | Phosphorylated Antibodies |
Description: | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] |
Immunogen: | A phospho specific peptide corresponding to residues surrounding Y1189/Y1190 of human INSR and Y1165/Y1166 of human IGF1R. |
Gene ID: | 3480/3643 |
Swiss prot: | P08069/P06213 |
Molecular weight: | 154kDa/155kDa/156kDa |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No:AB-AP0019
Manufacturer:ABclonal
Synonyms:CREB1;CREB;CREB-1
Applications:WB,IHC,IF,IP
Reactivity:Human,Rat
Host:Rabbit
Conjugate:No
€65,00 – €410,00
Catalog No:AB-AP0018
Manufacturer:ABclonal
Synonyms:CHEK1;CHK1
Applications:WB,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €410,00
Catalog No:AB-AP0016
Manufacturer:ABclonal
Synonyms:CDK1;CDC2;CDC28A;P34CDC2
Applications:WB,IHC,IF,IP
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €410,00
Catalog No:AB-AP0008
Manufacturer:ABclonal
Synonyms:AT1;ATA;ATC;ATD;ATDC;ATE;TEL1;TELO1;ATM
Applications:WB,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €410,00
Catalog No:AB-AP0005
Manufacturer:ABclonal
Synonyms:AKT2;HIHGHH;PKBB;PKBBETA;PRKBB;RAC-BETA
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €410,00
Catalog No:AB-AP0001
Manufacturer:ABclonal
Synonyms:ABL;JTK7;p150;c-ABL;v-abl;CHDSKM;c-ABL1;ABL1;c-Abl;bcr/abl
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €410,00