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Western blot analysis of extract from 293 cells, using Phospho-IGF1R-Y1280 antibody (AP0368).|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.
Phospho-IGF1R-Y1280 Rabbit pAb
Catalog No：AB-AP0368
Manufacturer：ABclonal
Synonyms：IGF1R;CD221;IGFIR;IGFR;JTK13
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€150,00 – €410,00
| Product Name: | Phospho-IGF1R-Y1280 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding Y1280 of human IGF1R |
| Gene ID: | 3480 |
| Swiss prot: | P08069 |
| Molecular weight: | 154kDa |
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