Phospho-HDAC4-S246/HDAC5-S259/HDAC9-S220 Rabbit pAb
Catalog No:AB-AP0280
Manufacturer:ABclonal
Synonyms:HDAC4/HDAC5/HDAC9
Applications:WB,IHC
Reactivity:Human
Host:Rabbit
Conjugate:No
€150,00 – €410,00
Product Name: | Phospho-HDAC4-S246/HDAC5-S259/HDAC9-S220 Rabbit pAb |
Category: | Phosphorylated Antibodies |
Description: | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008] |
Immunogen: | A phospho specific peptide corresponding to residues surrounding S246 of human HDAC4 |
Gene ID: | 9759/10014/9734 |
Swiss prot: | P56524/Q9UQL6/Q9UKV0 |
Molecular weight: | 57-65kDa/97-122kDa |
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