Phospho-ESPL1-S1126 Rabbit pAb
Catalog No：AB-AP0469
Manufacturer：ABclonal
Synonyms：ESPL1;ESP1;SEPA;separin
Applications：WB,IF
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €410,00
| Product Name: | Phospho-ESPL1-S1126 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]).[supplied by OMIM, Nov 2010] |
| Immunogen: | A synthetic phosphorylated peptide around S1126 of human ESPL1 (NP_036423.4). |
| Gene ID: | 9700 |
| Swiss prot: | Q14674 |
| Molecular weight: | 197kDa/233kDa |
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