Phospho-CAD-S1859 Rabbit pAb
Catalog No：AB-AP0884
Manufacturer：ABclonal
Synonyms：CAD;CDG1Z;EIEE50;GATD4
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €410,00
| Product Name: | Phospho-CAD-S1859 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Immunogen: | A synthetic phosphorylated peptide around S1859 of human CAD (NP_004332.2). |
| Gene ID: | 790 |
| Swiss prot: | P27708 |
| Molecular weight: | 242kDa |
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